We are an analytical chemistry lab with highly interdisciplinary research. On the one hand, we aim to develop physiologically relevant organ/tissue models to speed up biomedical research and drug development. On the other hand, we develop novel analytical methods (e.g., liquid chromatography-mass spectrometry) to study how extracellular matrices modulate cell functions via metabolomics and proteomics. After the pandemic lockdown, we initiated a new research direction to develop wearable biochemical sensors for invasive and continuous health monitoring with microfluidics, electrochemistry, and spectroscopy.